Bitte aktualisieren Sie Ihren Browser zur korrekten Anzeige dieser Webseite.

Navigating Into The Body

Living Bacteria as a Drug Delivery System

Micro- and nano-scale engineering is an emerging field with the potential to tackle some of today’s most crucial challenges in medicine. In particular, recent research showed how micro-nano-scale medicine could play a game-changing role in cancer diagnostics and treatment.

Let us imagine that magnetic bacteria flowing through the human body until they reach a tumor. What if such type of living bacteria could serve as a drug delivery system to locally treat cancer while being externally controlled? Is it fiction? Not really.

Together with the Responsive Biomedical Systems Laboratory (RBSL) at ETH Zürich, directed by the Professor Simone Schürle-Finke, I developed a method to build a three-dimensional world to illustrate this complex scientific process. The result shows how magnetotactic bacteria can navigate into the body and go out through blood vessels into the tumor by the use of external magnetic fields. The visualization of this process aims at communicating the research in an effective way and aiding future public acceptance for this new fascinating method.

Sonia Monti
BA-Diplome 2020

Design Mentor
Alessandro Holler

Cooperation Partner
Prof. Dr. Simone Schürle-Finke
Responsive Biomedical Systems lab (RBSL),
ETH Zürich

Cubic representation of extracellular matrix (ECM) and blood vessels.
Cubic representation of extracellular matrix (ECM) and blood vessels.
Representation of MTB in the bloodstream.
Representation of MTB in the bloodstream.
Experiment to represent the blood flow. The focus was on the size and on the quantity of the blood cells.
Experiment to represent the blood flow. The focus was on the size and on the quantity of the blood cells.
Building a three-dimensional MTB with attached liposomes.
Building a three-dimensional MTB with attached liposomes.